Experts

The 3Rs Centre Utrecht: connecting the 3Rs and the NAMs
Expert interviews
Innovation

The 3Rs Centre Utrecht: connecting the 3Rs and the NAMs

This animation of the 3Rs Centre Utrecht shows the differences, but also the similarities, between the 3Rs (Replacement, Reduction, Refinement of animal testing) approach and the NAMs (New Approach Methodologies) approach when trying to replace or reduce experimental animal use.
02:355 months ago
Stichting Proefdiervrij: Collaboration is key
Expert interviews
HealthInnovationPolicy

Stichting Proefdiervrij: Collaboration is key

At Stichting Proefdiervrij (the Dutch society for the replacement of animal testing) we believe that collaboration is essential for the development and implementation of animal-free models. In this video we introduce a few of the ways in which we, as an NGO, collaborate with researchers to reach our goal: the complete replacement of all test on animals
02:072 years ago
Monique Janssens: Why we need the Transition towards Animal-free Innovations
Expert interviews
HelpathonsPolicy

Monique Janssens: Why we need the Transition towards Animal-free Innovations

Why is there a Transition towards Animal-free Innovations, while we have the 3Rs, including Replacement? Well, there is a difference. Animal experiments should no longer be the golden standard of reference. We should not ask: Is this animal-free method good enough to replace animal experiments? But: What is the research question, and how do I get the best answer, preferably without animals? I know that many researchers are doing this already. But we can do even more! It’s also about involving the full chain of parties, including patients, financers, legislators and companies. That is why the transition movement works with interdisciplinary networks and Helpathons. The transition helps to innovate, to accelerate and to implement. At the same time, there is no need to throw the 3Rs overboard. Actually, we owe applying them to the lab animals of today. But by innovating we can develop even more new practices in research and education that bring about better results for science in less time and often with less costs. Without using animals.
02:373 years ago
Daniela Salvatori, TPI Utrecht: We aim for better science with less animals
Expert interviews
HealthEducation

Daniela Salvatori, TPI Utrecht: We aim for better science with less animals

Prof. dr. Daniela Salvatori, chair of TPI Utrecht, presents the aims of the local TPI group and invites all who want to share their ideas or questions on the transition towards animal-free innovations to get in touch via uu.nl/tpi.
02:233 years ago
Elly Hol, UMC Utrecht: Choosing the right model for your research question
Expert interviews
HealthInnovation

Elly Hol, UMC Utrecht: Choosing the right model for your research question

Prof. dr. Elly Hol (neuroscientist) talks about the opportunities for conducting animal-free research in Utrecht. She explains why it is necessary to use animal models next to cell-based models, for example for her Alzheimer research.
00:593 years ago
Kirsten Baken, VITO: Human biomonitoring
Expert interviews
HealthToxicology

Kirsten Baken, VITO: Human biomonitoring

Kirsten Baken discusses biomonitoring as part of the HBM4EU project (https://www.hbm4eu.eu). Human biomonitoring is an important component for a new way of doing risk assessment, based on human data. Human-based NAMs can also be informative for human biomonitoring. An example of the use of human biomarkers can be found here (https://www.sciencedirect.com/science/article/pii/S0013935119302658).
01:274 years ago
Janny van den Eijnden - van Raaij, hDMT consortium: OoC models, a game changing innovation
Expert interviews
HealthIn vitroOrgan-on-Chip

Janny van den Eijnden - van Raaij, hDMT consortium: OoC models, a game changing innovation

The Institute for human Organ and Disease Model technologies (hDMT) is a precompetitive non-profit technological R&D institute, initiated in the Netherlands. hDMT integrates state-of-the-art human stem cell technologies with top level engineering, physics, chemistry, biology, clinical and pharmaceutical expertise from academia and industry to develop and valorize human organ and disease models-on-a-chip. More information on: www.hdmt.technology , www.h2020-orchid.eu , and www.euroocs.eu .
01:164 years ago
Glenn Embrechts, European Schoolnet: Reinventing education with project based learning
Expert interviews
Education

Glenn Embrechts, European Schoolnet: Reinventing education with project based learning

Skills in Science, Technology, Engineering and Mathematics (STEM) are becoming an increasingly important part of basic literacy in today's knowledge economy. European Schoolnet is at the forefront of the debate on how to attract more people to science and technology to address the future skills gap that Europe is facing. STEM is one of European Schoolnet's major thematic domains. We have been involved in more than 30 STEM education initiatives, financed through European Schoolnet's Ministry of Education members, industry partners, or by the European Union's funding programmes. More information on social media: Social media: https://m.facebook.com/labonderwijs and https://www.instagram.com/lab_gedrevenonderwijs/ .
02:244 years ago
Erwin Roggen, ToxGen Solutions: Applying animal free testing approaches
Expert interviews
HealthToxicologyIn vitro

Erwin Roggen, ToxGen Solutions: Applying animal free testing approaches

Erwin Roggen explains his role as pioneer in the development of technologies for animal-free application. His product, ToxGenSolutions, provides test methods required for modern testing and assessment of compounds and products. It builds on a virtual generic platform of leading test and technology developers providing novel technologies addressing key events in adverse outcome pathways.
01:074 years ago
Charlotte Blattner, Harvard Law School: Transition needs community efforts
Expert interviews
Policy

Charlotte Blattner, Harvard Law School: Transition needs community efforts

Charlotte Blattner is a visiting researcher at Harvard Law School on the Animal Law & Policy Program and explains that a transition is needed to move away from animal testing. This transition needs to be a just transition, a community effort where all stakeholders are involved to replace animal testing for animal-free innovations.
01:064 years ago
Brett Lidbury, The Australian National University: Using machine learning to predict human health
Expert interviews
In silico

Brett Lidbury, The Australian National University: Using machine learning to predict human health

Brett Lidbury is associate professor at the Research School of Population Health of The Australian National University. He applies machine learning to make predictions about health using human big data rather than animal experiments. For more information, go to www.anu.edu.au and search “Lidbury”.
01:574 years ago
Tox 21: A New Way to Evaluate Chemical Safety and Assess Risk
Expert interviews
ToxicologyIn silicoPolicy

Tox 21: A New Way to Evaluate Chemical Safety and Assess Risk

Tox21 is a US federal research collaboration focused on driving the evolution of Toxicology in the 21st Century by developing methods to rapidly and efficiently evaluate the safety of commercial chemicals, pesticides, food additives/contaminants, and medical products. The goals of Tox21 are to (1) identify mechanisms of chemically-induced biological activity; (2) prioritize chemicals for more extensive testing; and (3) develop more relevant and predictive models of in vivo toxicological responses.
06:294 years ago